화학공학소재연구정보센터
Journal of Chemical Thermodynamics, Vol.126, 126-127, 2018
Commentary on the "Measurement and prediction of dabigatran etexilate mesylate Form II solubility in mono-solvents and mixed solvents"
Errors are discovered regarding the published equation coefficients of Xiao and co-workers [J. Chem. Thermodynamics 103 (2016) 44-50] for mathematically describing the solubility behaviour of dabigatran etexilate mesylate (DEM) Form II in five mono-solvents using the modified Apelblat equation. The back-calculated values using the published equation coefficients are not the mole fraction solubility as stated in the published paper. The authors inadvertently minified 10(6) times the equation coefficients B. (C) 2018 Elsevier Ltd.