This publication concerns the design of advanced nanostructured inorganic materials using supercritical fluids. A brief overview of the different experimental and numerical tools, which are now available for the scientific community and engineers, is proposed giving access to a better understanding but also a better control on material synthesis. The versatility of the supercritical fluids route for the preparation of different natures of inorganic materials is emphasized based on the access to numerous solvents, precursors and their associated chemistries. It is possible to produce materials with physicochemical properties, which can not be obtained with other routes and at large scale. All these chemistries give access to a wide range of nanobricks opening a new area for the preparation of advanced materials by design through the development of one pot multistep processes.