We report on the structural, magnetic, and bioactive properties of TiO2-modified silicate glasses. Addition of TiO2 and heat treatment, shows remarkable and distinguishable effect on the properties of the glasses. Growth of titania-modified magnetic nanocrystals played effective role in the evolution of magnetic properties of the glass-ceramics. Some of the samples exhibit superparamagnetic nature, while others are found to be antiferromagnetic. Interestingly, after heat treatment the magnetization trend of the samples reversed. The invitro bioactivity of these glass-ceramics was accessed by the formation of bone- like apatite structures on their surfaces after immersion in simulated body fluid. The magnetic properties along with the bioactivity of present glass-ceramics indicate their usefulness in the magnetically induced hyperthermia treatment of cancer.