화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Korean Journal of Chemical Engineering, Vol.35, No.9, 1765-1778, September, 2018
DOI10.1007/s11814-018-0102-0  Export Citation
Recent advances in protein-based nanoparticles
Eun Jung Lee†
  • Department of Chemical Engineering, School of Applied Chemical Engineering, Kyungpook National University, Daegu 41566, Korea
E-mail:
Certain naturally occurring proteins consist of a number of subunit building blocks that are capable of selfassembling to form nanoscale particles with highly organized, symmetrical, and homogeneous structures. These protein- based nanoparticles have high surface/volume ratios and other favorable properties, including mono-dispersibility, high stability, low toxicity, biocompatibility, biodegradability, and capacity for easy genetic and chemical modification. Thus, these particles have attracted considerable research attention and have been manipulated for various applications in different fields. This review describes the engineering of existing protein nanoparticles, with a particular focus on scientific advances in diverse applications, including bioassays, molecular imaging diagnostics, drug delivery, biocatalysis, and materials science. In addition, barriers for the widespread industrial use of such nanoparticles and outlook for the design and creation of novel self-assembled protein-based nanoparticles are considered.
Keywords:Protein-based Nanoparticles;Functionalization;Diagnostics;Drug Delivery;Biocatalysis;Materials Science
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