화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.66, 107-115, October, 2018
DOI10.1016/j.jiec.2018.05.019  Export Citation
Synthesis and characterization of magnetic molecularly imprinted polymers for enrichment of sanguinarine from the extraction wastewater of M. cordata
Ming Zhong†, Yan-Hong Wang, Lu Wang, Rui-Qing Long, and Chun-Lin Chen1, †
  • School of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang, Hunan 414006, China
  • 1Ningbo Institute of Materials Technology & Engineering, Chinese Academy of Sciences, 1219 Zhongguan West Road, Ningbo 315201, China
E-mail:,
A novel and efficient pretreatment method is proposed for the enrichment of sanguinarine (SA) from the extraction wastewater of Macleaya cordata (Willd) R. Br. using magnetic molecularly imprinted polymers (MMIPs) as solid phase adsorbent. The obtained MMIPs were synthesized by molecular imprinted technology and were well characterized with TEM, FT-IR, XRD, TGA, and VSM. The adsorption capacity and selectivity of MMIPs were also investigated. The results showed that the obtained MMIPs were core. shell spherical morphologies with an average diameter of 300 nm. The adsorption experiments showed that the MMIPs exhibited an almost three times higher adsorption capacity towards SA (Qmax = 12.24 mg/ g) than magnetic molecularly non-imprinted polymers (MNIPs) (Qmax = 4.15 mg/g). The calculated parameters of adsorption isotherms and kinetics suggested that the adsorption process matched the Langmuir adsorption isotherm and pseudo-second-order kinetics model. The thermodynamic parameters were calculated, indicating that the adsorption process was spontaneous (ΔG298K = -3.24 kJ/mol). The selectivity experiment showed that the MMIPs displayed higher selective adsorption capacity for SA compared to its reference compounds. Moreover, the MMIPs were applied to enrich SA from the extraction wastewater of M. cordata. The proposed method could provide an effective, simple and environmentally friendly way to identify and enrich SA from the extraction wastewater of M. cordata.
Keywords:Magnetic molecularly imprinted polymers;Sanguinarine;Solid phase adsorbent;Adsorption;Enrichment
  1. Galadari S, Rahman A, Pallichankandy S, Thayyullathil F, Phytomedicine, 34, 143 (2017)
  2. Zhang F, Xie J, Wang G, Zhang G, Yang H, J. Cell. Physiol., 233, 4626 (2018)
  3. Niu X, Fan T, Li W, Xing W, Huang H, Eur. J. Pharmacol., 689, 262 (2012)
  4. Zabka A, Winnicki K, Polit JT, Mazewski J, Plant Physiol. Biochem, 112, 193 (2017)
  5. Eun JP, Koh GY, Biophys. Res. Commun., 37, 618 (2004)
  6. Deroussent A, Re M, Hoellinger H, Cresteil T, J. Pharm. Biomed. Anal., 52, 391 (2010)
  7. Zhong M, Huang K, Zeng J, Li S, Zhang L, J. Cent. South Univ. Technol., 17, 472 (2010)
  8. Colombo ML, Bosisio E, Pharm. Res., 33, 127 (1996)
  9. Sarkar SN, Nature, 265, 162 (1948)
  10. Williams MK, Dalvi SS, Dalvi RR, Vet. Hum. Toxicol., 42, 196 (2000)
  11. Choy CS, Cheah KP, Chiou HY, Li JS, Liu YH, Yong SF, Chiu WT, Liao JW, Hu CM, J. Appl. Toxicol., 28, 945 (2008)
  12. Hoellinger H, Re M, Deroussent A, Singh RP, Cresteil T, J. Chromatogr. B, 799, 195 (2004)
  13. Chen YZ, Liu GZ, Shen Y, Chen B, Zeng JG, J. Chromatogr. A, 1216, 2104 (2009)
  14. Zuo Z, Zheng Y, Liang Z, Liu Y, Tang Q, Liu X, Zhao Z, Zeng J, Rapid Commun. Mass Spectrom., 13, 397 (2017)
  15. Xie H, Yang J, Feng S, Cheng P, Zeng J, J. Chromatogr. B, 985, 124 (2015)
  16. Gu GH, Yang DJ, Wang SY, Zeng W, Wang W, Yuan JS, Acta Chromatogr., 29, 121 (2017)
  17. Yoshimatsu K, Kiuchi F, Shimomura K, Makino Y, Chem. Pharm. Bull., 53, 1446 (2005)
  18. He Y, Huang Y, Jin Y, Liu X, Liu G, Zhao R, ACS Appl. Mater. Interfaces, 6, 9634 (2014)
  19. Wu Q, Li M, Huang Z, Shao Y, Bai L, Zhou L, J. Ind. Eng. Chem., 60, 268 (2018)
  20. Li J, Zhang X, Liu Y, Tong H, Xu Y, Liu S, Talanta, 117, 281 (2013)
  21. Luo J, Sun J, Huang J, Liu X, J. Chem. Eng., 283, 1118 (2016)
  22. Wang Q, Chen M, Zhang H, Wen W, Zhang X, Wang S, Sens. Actuators B-Chem., 222, 264 (2016)
  23. Song H, Wang Y, Zhang L, Tian L, Tian L, Luo J, Zhao N, Han Y, Zhao F, Ying X, Li Y, Bioanal. Chem., 409, 6509 (2017)
  24. Zhang ZJ, Zhang XH, Liu BW, Liu JW, J. Am. Chem. Soc., 139(15), 5412 (2017)
  25. Muhammad P, Tu X, Liu J, Wang Y, Liu Z, ACS Appl. Mater. Interfaces, 9, 12082 (2017)
  26. Singh B, Chauhan N, Acta Biomater., 4, 1244 (2008)
  27. Miura C, Matsunaga H, Haginaka J, J. Pharm. Biomed. Anal, 114, 139 (2015)
  28. Cao Z, Ma W, Dai J, Pan J, Wei X, Song Z, Li C, Yan Y, Nanosci. Nanotechnol. Lett., 6, 657 (2014)
  29. Yin J, Yang G, Chen Y, J. Chromatogr. A, 1090, 68 (2005)
  30. Ma Y, Pan G, Zhang Y, Guo X, J. Mol. Recognit., 26, 240 (2013)
  31. Zhu R, Zhao W, Zhai M, Wei F, Cai Z, Sheng N, Hu Q, Anal. Chim. Acta, 658, 209 (2010)
  32. Gao B, He X, Jiang Y, Wei J, Suo H, Zhao C, J. Sep. Sci., 37, 3753 (2014)
  33. Lu Y, Yan CL, Gao SY, Appl. Surf. Sci., 255(12), 6061 (2009)
  34. Xia R, Hao Y, Zhang L, Cui X, Liu D, Zhang M, Tang Y, Zheng Y, J. Chem. Eng., 284, 139 (2016)
  35. Zhang M, Zhang X, He X, Chen L, Zhang Y, Nanoscale, 4, 3141 (2012)
  36. Xia R, Mu X, Hao Y, Zhang L, Zhang J, Tang Y, J. Mater. Chem. B, 2, 1733 (2014)
  37. Xia R, Cui X, Hao Y, Zhang L, Liu D, Tang Y, Food Chem., 194, 1040 (2016)
  38. Lin ZK, He QY, Wang LT, Wang XD, Dong QX, Huang CJ, J. Hazard. Mater., 252, 57 (2013)
  39. Yao GH, Liang RP, Huang CF, Wang Y, Qiu JD, Anal. Chem., 85, 11944 (2013)
  40. Liu XY, Yu D, Yu YC, Ji SJ, Appl. Surf. Sci., 320, 138 (2014)
  41. Xie X, Chen L, Pan X, Wang S, J. Chromatogr. A, 1405, 32 (2015)
  42. Li N, Qi L, Shen Y, Qiao J, Chen Y, ACS Appl. Mater. Interfaces, 6, 17289 (2014)
  43. Zhang T, Zhang XF, Yan XJ, Kong LY, Zhang GC, Liu HO, Qiu JS, Yeung KL, Chem. Eng. J., 228, 398 (2013)