The morphological and textural characteristics of hydro-compacted nanosilicas (wetted by various water amounts in the range of h(cp) = 0.3-5.0 g per gram of dry silica, and then dried) were analyzed using low-temperature H-1 NMR spectroscopy, SAXS, SEM, TEM, IR spectroscopy, and nitrogen adsorption methods. The results of the hydro-compaction of nanosilica A-300 depend strongly on the h(cp), value, which can be varied to control reorganization of secondary and ternary structures formed by nanoparticles. The compaction is accompanied by non-monotonic changes in the textural characteristics; however, the nanoparticles per se are practically not affected by the treatment. At h(cp )<= 1 g/g, the reorganization of secondary/ternary structures does not lead to diminution of the specific surface area (S-BET); however, at h(cp) >= 1.5 g/g, the S-BET value decreases, but the pore volume increases despite the empty volume of the powder decreases from 21.8 cm(3)/g for initial A-300 (bulk density rho(b) = 0.045 g/cm(3)) to 3.45 cm(3)/g on compaction at h(cp) = 4.5 g/g (rho(b) = 0.256 g/cm(3)). The structural reorganization of hydro-compacted powders is possible after addition of new water amount. This suggests that the chemical bonds between neighboring nanoparticles do not practically form upon the hydro-compaction. Thus, hydro-compacted nanosilica can lose a dust-forming property but remains active with respect to nanoparticles mobility and possibility of reorganization of the secondary structures with nanoparticles.