This research paper describes the preparation, characterization and the hydrogen peroxide decomposition activity of a series of nano-crystalline Ag-Cr-O catalysts obtained by calcining a parent mixture of silver acetate and ammonium dichromate. This parent has been calcined for 1 h, in air, at the temperature range of 200-700 degrees C. The characterization of the nano-crystalline Ag-Cr-O catalysts was performed using a series of physico-chemical analyses including TGA-DTA, XRD, FTIR, SEM, TEM, and XPS. The results revealed that heat treatment brought about a significant-phase formation, Ag2Cr2O7 is formed at 200 degrees C and a mixture of Ag2CrO4 and Cr2O3 are formed over the calcination temperature range of 300-500 degrees C. AgCrO2 stars to form at 500 degrees C and becomes a major phase at the range 600-700 degrees C with a noticeable segregation of metallic silver. The activity of the different nano-crystalline Ag-Cr-O catalysts was tested for hydrogen peroxide decomposition at the temperature range 35-50 degrees C. The kinetic data showed a direct dependence on the calcination temperature and it was correlated with the formed surface redox-couples.