Based on a class of industrial processes, a new distributed fault diagnosis approach and a collaborative operational fault tolerant control law are proposed for an irreversible interconnected stochastic distribution control (SDC) system with boundary conditions. This control method is different from the existing collaborative fault tolerant controllers which enable the output probability density function (PDF) to track a desired PDF as close as possible. When fault occurs, a setpoint redesigned fault tolerant approach is adopted to accommodate the fault instead of reconstructing the controller. An augmented PID nominal controller and a setpoint compensation item with linear structure are used to obtain a collaborative operational fault tolerant controller via solution of linear matrix inequalities (LMIs). Simulations are included to show the effectiveness of the proposed algorithms where encouraging results have been obtained. (C) 2018 Elsevier Ltd. All rights reserved,