A multicomponent lattice Boltzmann model for simulation of phase change with heat transfer is proposed in this paper. The model combines a thermal single-component phase change model with a multicomponent model, and the two models are verified separately. The combined model is used to simulate the phase change process of one component in multicomponent fluid with heat transfer. The phase change of a static droplet wrapped in another component and the phase change of fluid flowing into another component with gravity effect are solved numerically based on the proposed model. The ratio of density before and after phase change in the simulation is close to 10. Distribution of temperature field and flow field during phase transition is discussed. Simulation results also show the influence of specific heat capacity on the phase change rate.