In this paper, an integrated liquefied natural gas (LNG) production process, carbon dioxide separation and liquefaction, and fresh water production is proposed and analyzed. The hybrid system consists of three sections: power and heat generation by the process of combustion with pure oxygen, natural gas liquefaction with a two-stage refrigeration cycle (absorption refrigeration cycle and multi-component refrigerant), and multiple-effect distillation (MED) desalination. This integrated process produce 593.3 ton/h LNG, 84.62 ton/h carbon dioxide, and 74.58 ton/h fresh water. Exergy analysis shows that the highest exergy destruction is related to the shell and tube heat exchangers, which is about 38.8% and the lowest exergy destruction is related to the air coolers, 0.84%. Integrated process has an overall electrical efficiency (LHV Base) of 36.3%, a specific power of 0.179 kWh/kg LNG. Also the amount of energy consumed for producing carbon dioxide is 0.005 kWh/kg CO2, and gained output ratio (GOR) of 2.87 is achieved by three-stage MED desalination. A sensitivity analysis is done to investigate and identify the important parameters affecting the integrated process performance. (C) 2018 Elsevier Ltd. All rights reserved.