Hybrid bitumen extraction (HBE) at ambient conditions has potential, as an alternative to the currently used modified Clark hot water extraction (CHINE), to reduce thermal energy intensity and greenhouse gas emissions for bitumen extraction from mined ore. Importantly, this extraction method could be retrofitted to the current commercial process. This research focuses on the extent of solvent loss in the sand tailings, which is the most important issue associated with the success and commercialization of HBE. In this work, a series of bench-scale HBE tests were conducted under various conditions, and the solvent content in the tailings was determined. Results suggest that the amount of solvent in the tailings depends largely on the processability of oil sand ore and the type and dosage of solvent used to soak the ore in the HBE. With a good processing ore, for which over 90% bitumen recovery was obtained, solvent losses to tailings were below the regulated volatile organic compound loss limit, without the use of a tailings solvent recovery unit. The correlation between solvent loss to tailings and unrecovered bitumen content is discussed.