CdSe nanocrystals, including quantum dots and quantum rods, are a research hotspot in nanomaterials. Recently, it has been found that two-dimensional CdSe semiconductor nanobelts show a unique quantum confinement effect owing to their homogeneous nanoscale thickness. In this study, a series of (CdSe)(n)center dot monoamine (n = 1, 2, and 4, monoamine = butylamine, hexylamine, and octylamine) layered inorganic/organic hybrid nanobelts was synthesized by the solvothermal method. These hybrids have a lamellar structure alternatively stacked along the c axis of their crystallites, which exhibit the typical preferred orientation for layered crystallites and isomorphous [CdSe] layers according to their X-ray diffraction patterns. The [CdSe] layer is a contracted (110) superlattice cell of wurtzite (WZ)-type CdSe with unit cell parameter relations of a approximate to root 3a(wz) and b approximate to c(wz), and a lamellar nanobelt morphology with the [010] growth direction. These ordered hybrids exhibit prominent split exciton absorption peaks and sharp band edge luminescence owing to the homogeneous thickness of the [CdSe] layers within the hybrids, all of which are comparable with reported WZ-type CdSe colloidal nanosheets and exhibit a prominent two-dimensional exciton quantum confinement effect. The solvothermal reaction was systematically investigated. The multiple stage amine de-intercalation topotactic process was revealed for the WZ-type CdSe nanobelts with the (CdSe)(n)center dot monoamine (n = 1, 2, and 4) hybrids as the intermediate phases. The solvothermal synthesis method (70-150 degrees C) is facile and milder than the traditional hot injection method (>200 degrees C). Therefore, these hybrids can be considered to be intermediate phases or precursors of WZ-type CdSe nanosheets with a topotactic intralayer [CdSe] structure and also a type of multiple quantum well with extremely thin [CdSe] layers orderly stacked among the monoamine insulating blocking layers.