Liquid-liquid equilibrium (LLE) data for ternary systems of water + 2,2,3,3-tetrafluoro-1-propanol + anisole/1-octanol were determined at temperatures of 298.2, 308.2, and 318.2 K under 101.3 kPa. The distribution coefficients and separation factors were calculated from experimental LLE data, which indicated that anisole/1-octanol extracted 2,2,3,3-tetrafluoro-1-propanol from aqueous solution with high efficiency. The consistency of the experimental LLE data was assessed by the Othmer-Tobias and Hand equations. Meanwhile, the NRTL and UNIQUAC models were successfully applied to regress and correlate the experimental data, presenting the root-mean-square deviations (RMSD) less than 1.0%. The relevant binary interaction parameters of these two models were also regressed.