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Journal of Chemical and Engineering Data, Vol.63, No.8, 2629-2636, 2018
Solubility of p-Aminobenzoic Acid Potassium in Organic Solvents and Binary (Water plus Isopropyl Alcohol) Mixture at Temperatures from (283.15 to 318.15) K
The solid-liquid equilibrium behavior of p-aminobenzoic acid potassium (KPAB) in pure organic solvents and binary (water + isopropyl alcohol) solvents were determined over the temperature range (283.15-318.15) K using a laser dynamic method. It was found that KPAB is easily dissolved in water, polyhydroxy alcohols and amides; slightly soluble in ethyl acetate, isopropyl alcohol, and n-propanol. The solubility of KPAB in both the mono- and binary mixed solvents increases with the increasing temperature, whereas it decreases with the rise of mole fraction of isopropyl alcohol in binary (water + isopropyl alcohol) mixed solvents. The solubility in pure solvents was correlated by the modified Apelblat equation, and the solubility in binary mixed solvents was correlated with the modified Apelblat equation and Combined Nearly Ideal Binary Solvent/Redlich-Kister (CNIBS/R-K) model. All the models give satisfactory correlation results with an average relative deviation (ARD) less than 2.5%, which provide basic data for the design of KPAB crystallization process and equipment.