화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.69, 455-463, January, 2019
DOI10.1016/j.jiec.2018.10.007  Export Citation
A facile, green synthesis of biomass carbon dots coupled with molecularly imprinted polymers for highly selective detection of oxytetracycline
Haochi Liu, Lan Ding†, Ligang Chen1, †, Yanhua Chen, Tianyu Zhou, Huiyu Li, Yuan Xu, Li Zhao, and Ning Huang
  • College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China
  • 1Department of Chemistry, College of Science, Northeast Forestry University, 26 Hexing Road, Harbin 150040, China
E-mail:,
Biomass carbon dots (CDs) prepared by sweet potato peels were superior fluorophores with low toxicity and excellent photostability. A novel designed fluorescence probe for specific recognition and sensitive detection of oxytetracycline (OTC) was fabricated with CDs and molecularly imprinted polymer (MIP). The quenching of CDs happened when rebinding with OTC due to electron-transfer induced fluorescence quenching mechanism. The fluorescence probe was successfully applied in honey with the recoveries ranging from 90.2% to 97.3%. The detection limit of OTC was 15.3 ng mL-1. This work provides promising perspectives that the development of fluorescent MIP will be valuable for rapid analysis in complex samples.
Keywords:Biomass carbon dots;Molecularly imprinted polymers;Oxytetracycline;Fluorescence probe;Honey
  1. Ghodsi J, Rafati AA, Shoja Y, Sens. Actuators B-Chem., 224, 692 (2016)
  2. GB 14963-2011. National Standard of the People’s Republic of China.
  3. Lv YK, Wang LM, Yang L, Zhao CX, Sun HW, J. Chromatogr. A, 1227, 48 (2012)
  4. Wang L, Yang H, Zhang C, Mo Y, Lu X, Anal. Chim. Acta, 619, 54 (2008)
  5. Kim YS, Kim JH, Kim IA, Lee SJ, Jurng J, Gu MB, Biosens. Bioelectron., 26, 1644 (2010)
  6. Chen Y, Kong D, Liu L, Song S, Kuang H, Xu C, Food Anal. Methods, 9, 905 (2016)
  7. Mookantsa SO, Dube S, Nindi MM, Talanta, 148, 321 (2016)
  8. Gajda A, Jablonski A, Bladek T, Posyniak A, J. Agric. Food Chem., 65, 494 (2017)
  9. He J, Li G, Hu Y, Microchim. Acta, 184, 2365 (2017)
  10. Gao C, Liu Z, Chen JQ, Yan ZY, Luminescence, 28, 378 (2013)
  11. Xu SH, Li XL, Mao YN, Gao T, Feng XY, Luo XL, Anal. Bioanal. Chem., 408, 2955 (2016)
  12. Sun YP, Zhou B, Lin Y, Wang W, Fernando KAS, Pathak P, Meziani MJ, Harruff BA, Wang X, Wang HF, Luo PJG, Yang H, Kose ME, Chen BL, Veca LM, Xie SY, J. Am. Chem. Soc., 128(24), 7756 (2006)
  13. Yuan F, Wang Z, Li X, Li Y, Tan Z, Fan L, Yang S, Adv. Mater., 29, 160443 (2017)
  14. Baker SN, Baker GA, Angew. Chem.-Int. Edit., 49, 6726 (2010)
  15. Lee H, Park R, Lee HW, Hong Y, Lee Y, Park SH, Jung SC, Yoo KS, Jeon JK, Park YK, Carbon Lett., 19, 79 (2016)
  16. Lee HW, Kim YM, Kim S, Ryu C, Park SH, Park YK, Carbon Lett., 26, 1 (2018)
  17. Lee HW, Park R, Park SH, Jung SC, Jeon JK, Kim SC, Chung JD, Choi WG, Park YK, Carbon Lett., 18, 49 (2016)
  18. Cha JS, Park SH, Jung SC, Ryu C, Jeon JK, Shin MC, Park YK, J. Ind. Eng. Chem., 40, 1 (2016)
  19. Li G, Zhu W, Zhu L, Chai X, Korean J. Chem. Eng., 33(7), 2215 (2016)
  20. Wang H, Xia W, Lu P, Korean J. Chem. Eng., 34(6), 1867 (2017)
  21. Cheng C, Shi Y, Li M, Xing M, Wu Q, Mater. Sci. Eng. C-Biomimetic Supramol. Syst., 79, 473 (2017)
  22. Wei J, Zhang X, Sheng Y, Shen J, Huang P, Guo S, Pan J, Liu B, Feng B, New J. Chem., 38, 906 (2014)
  23. Chen L, Wang X, Lu W, Wu X, Li J, Chem. Soc. Rev., 45, 2137 (2016)
  24. Chen L, Li B, Food Chem., 141, 23 (2013)
  25. Liu H, Wu D, Zhou K, Wang J, Sun B, Food Chem., 211, 34 (2016)
  26. Chantada-Vazquez MP, Sanchez-Gonzalez J, Pena-Vazquez E, Tabernero MJ, Bermejo AM, Bermejo-Barrera P, Moreda-Pineiro A, Biosens. Bioelectron., 75, 213 (2016)
  27. Zhou Y, Qu ZB, Zeng YB, Zhou TS, Shi GY, Biosens. Bioelectron., 52, 317 (2014)
  28. Chao MR, Hu CW, Chen JL, Biosens. Bioelectron., 61, 471 (2014)
  29. Chen L, Xu S, Li J, Chem. Soc. Rev., 40, 2922 (2011)
  30. Hou J, Li H, Wang L, Zhang P, Zhou T, Ding H, Ding L, Talanta, 146, 34 (2016)
  31. Hou J, Yan J, Zhao Q, Li Y, Ding H, Ding L, Nanoscale, 20, 9558 (2013)
  32. Dai J, Dong X, Cortalezzi MF, Microchim. Acta, 184, 1369 (2017)
  33. Xu S, Lu H, Biosens. Bioelectron., 85, 950 (2016)
  34. Wang H, Yi J, Velado D, Yu Y, Zhou S, ACS Appl. Mater. Interfaces, 7, 15735 (2015)
  35. Koesukwiwat U, Jayanta S, Leepipatpiboon N, J. Chromatogr. A, 1140, 147 (2007)
  36. Grabolle M, Spieles M, Lesnyak V, Gaponik N, Eychmuller A, Resch-Genger A, Anal. Chem., 81, 6285 (2009)
  37. Mao Y, Bao Y, Han DX, Li FH, Niu L, Biosens. Bioelectron., 38, 55 (2012)
  38. Ko HY, Chang YW, Paramasivam G, Jeong MS, Cho S, Kim S, Chem. Commun., 49, 10290 (2013)
  39. Shao X, Gu H, Wang Z, Chai X, Tian Y, Shi G, Anal. Chem., 85, 418 (2013)
  40. Chemtob A, Ni L, Croutxe-Barghorn C, Boury B, Chem. Eur. J., 20, 1790 (2014)
  41. Hassanzadeh J, Khataee A, Oskoei YM, Fattahi H, Bagheri N, New J. Chem., 41, 10659 (2017)
  42. Wei JM, Zhang X, Sheng YZ, Shen JM, Huang P, Guo SK, Pan JQ, Feng BX, Mater. Lett., 123, 107 (2014)
  43. Gedda G, Lee CY, Lin YC, Wu HF, Sens. Actuators B-Chem., 224, 396 (2016)
  44. Iqbal A, Tian Y, Wang X, Gong D, Guo Y, Iqbal K, Wang Z, Liu W, Qin W, Sens. Actuators B-Chem., 237, 408 (2016)
  45. Atchudan R, Edison TNJI, Sethuraman MG, Lee YR, Appl. Surf. Sci., 384, 432 (2016)
  46. Qiao Z, Wang Y, Gao Y, Li H, Dai T, Liu Y, Huo Q, Chem. Commun., 46, 8812 (2010)
  47. Yang X, Zhuo Y, Zhu S, Luo Y, Feng Y, Dou Y, Biosens. Bioelectron., 60, 292 (2014)
  48. Zhang Z, Li J, Wang X, Shen D, Chen L, ACS Appl. Mater. Interfaces, 7, 9118 (2015)
  49. Jalili R, Amjadi M, Sens. Actuators B-Chem., 255, 1072 (2018)
  50. Zu FL, Yan FY, Bai ZJ, Xu JX, Wang YY, Huang YC, Zhou XG, Microchim. Acta, 184, 1899 (2017)
  51. Vinas P, Balsalobre N, Lopez-Erroz C, Hernandez-Cordob M, J. Chromatogr. A, 1022, 125 (2004)
  52. Sun X, He X, Zhang Y, Chen L, Talanta, 79, 926 (2009)
  53. Yi ZX, Wu Q, Zhu Y, Ou M, Xu X, RSC Adv., 6, 89288 (2016)
  54. Peres GT, Rath S, Reyes FGR, Food Control, 21, 620 (2010)
  55. Tsukamoto T, Yasuma M, Yamamoto A, Hirayama K, Kihou T, Kodama S, Inoue Y, J. Sep. Sci., 32, 3591 (2009)
  56. Pena A, Pelantova N, Lino CM, Silveira MIN, Solich P, J. Agric. Food Chem., 53, 3784 (2005)