화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.70, 402-411, February, 2019
DOI10.1016/j.jiec.2018.11.003  Export Citation
An integrated strategy for extraction and pre-concentration of four astragalosides from Radix Astragali by a formulated surfactant aqueous system
Suixin Wang1, Jiao Jiao1, Xinyu Wang1, Qingyan Gai1, Ping Kou1, Wenjing Xu1, Meng Luo1, Chunjian Zhao1, and Yu-Jie Fu1, 2, †
  • 1Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University,, Harbin 150040, PR China
  • 2Advanced Innovation Center for Tree Breeding by Molecular Design, Beijing Forestry University, 100083, Beijing, PR China
E-mail:
Integrated and environmentally friendly methods for extraction and enrichment of natural products have gained increasing interests. The proposed preparation process provides the possibility that extraction and pre-concentration for astragalosides from Radix Astragali roots can be conducted with the surfactant aqueous system in one single procedure. The formulated surfactant system composing of 2% TX-114 as surfactant and 0.03% (w/v) of Gemini 16-5-16 as co-surfactant showed higher extraction efficiency with ultrasonic-assisted method and four astragalosides could be enriched by the cloud point phenomenon of surfactant. This work represents a valuable alternative for the eco-friendly extraction and enrichment of secondary metabolites from plants.
Keywords:Formulated surfactant;Extraction;Pre-concentration;Astragalosides;Radix Astragali
  1. Qi LW, Cao J, Li P, Yu QT, Wen XD, Wang YX, Li CY, Bao KD, Ge XX, Cheng XL, J. Chromatogr. A, 1203, 27 (2008)
  2. Yin JY, Chan CL, Yu H, Lau YK, Han XQ, Cheng SW, Wong CK, Lau BS, Xie MY, Fung KP, Carbohydr. Polym., 87, 667 (2012)
  3. Song QH, Kobayashi T, Xiu LM, Hong T, Jongchol C, J. Ethnopharmacol., 73, 111 (2000)
  4. Shahzad M, Shabbir A, Wojcikowski K, Wohlmuth H, Gobe GC, Curr. Drug Targets, 17 (2015)
  5. Chen X, Wang DD, Wei T, He SM, Zhang GY, Wei QL, Exp. Ther. Med., 11, 2561 (2016)
  6. Zhao BS, Fu YJ, Wang W, Zu YG, Gu CB, Luo M, Efferth T, Innov. Food Sci. Emerg. Technol., 12, 577 (2011)
  7. Xu T, Feng G, Zhao B, Zhao J, Pi Z, Liu S, Song F, Liu Z, J. Chromatogr. B Anal. Technol. Biomed. Life Sci., 1048, 94 (2017)
  8. Zhao P, Su G, Xiao X, Hao E, Zhu X, Ren J, Toxicol. Lett., 182, 29 (2008)
  9. Lin YW, Chiang BH, Process Biochem., 43(3), 244 (2008)
  10. Cho WC, Leung KN, Cancer Lett., 252, 43 (2007)
  11. Zheng KY, Choi RC, Guo AJ, Bi CW, Zhu KY, Du CY, Zhang ZX, Lau DT, Dong TT, Tsim KW, J. Pharm. Biomed. Anal., 70, 671 (2012)
  12. Zhang Q, Fong CC, Yu WK, Chen Y, Wei F, Koon CM, Lau KM, Leung PC, Lau CB, Fung KP, Yang M, Phytomed. Int. J. Phytother. Phytopharmacol., 20, 9 (2012)
  13. Lee JS, Kim HG, Han JM, Kim DW, Yi MH, Son SW, Kim YA, Lee JS, Choi MK, Son CG, J. Ethnopharmacol., 153, 782 (2014)
  14. Yin G, Cheng X, Tao W, Dong Y, Bian Y, Zang W, Tang D, J. Pharm. Biomed. Anal., 148, 224 (2018)
  15. Lee SM, Jeong JS, Kwon HJ, Hong SP, J. Chromatogr. B Anal. Technol. Biomed. Life Sci., 1070, 76 (2017)
  16. Yan MM, Liu W, Fu YJ, Zu YG, Chen CY, Luo M, Food Chem., 119, 1663 (2010)
  17. Zhou RN, Song YL, Ruan JQ, Wang YT, Yan R, Drug Metab. Pharmacokinet., 27, 586 (2012)
  18. Peng X, Xu HX, Yuan XZ, Leng LJ, Meng Y, Sep. Purif. Technol., 160, 117 (2016)
  19. Abbasi S, Radi M, Food Chem., 194, 972 (2016)
  20. Loison C, Mareschal M, Schmid F, J. Chem. Phys., 121(4), 1890 (2004)
  21. Amiri S, Abbasi S, Ezzatpanah H, Hosseini E, Agro Food Ind. Hi Tech., 24, 72 (2013)
  22. Lamichhane S, Bal Krishna KC, Sarukkalige R, J. Environ. Manage., 199, 46 (2017)
  23. Kundu K, Guin G, Paul BK, J. Colloid Interface Sci., 385, 96 (2012)
  24. Zhang Y, Huang XR, Huang F, Li YZ, Qu YB, Gao PJ, Colloids Surf. B: Biointerfaces, 65, 50 (2008)
  25. Tzialla AA, Taha AA, Kalogeris E, Stamatis H, Biotechnol. Lett., 31(9), 1451 (2009)
  26. Quina FH, Hinze WL, Ind. Eng. Chem. Res., 38(11), 4150 (1999)
  27. Kheirandish S, Ghaedi M, Dashtian K, Jannesar R, Montazerozohori M, Pourebrahim F, Zare MA, J. Colloid Interface Sci., 500, 241 (2017)
  28. Kheirandish S, Ghaedi M, Dashtian K, Pourebrahim F, Ultrason. Sonochem., 39, 798 (2017)
  29. Asfaram A, Ghaedi M, Abidi H, Javadian H, Zoladl M, Sadeghfar F, Ultrason. Sonochem., 44, 240 (2018)
  30. Bahrani S, Ghaedi M, Dashtian K, Ostovan A, Mansoorkhani MJK, Salehi A, J. Chromatogr. B Anal. Technol. Biomed. Life Sci., 1067, 45 (2017)
  31. Esumi K, Goino M, Koide Y, J. Colloid Interface Sci., 183(2), 539 (1996)
  32. Panda M, Kabir ud D, J. Mol. Liq., 187, 106 (2013)
  33. Kolaei M, Dashtian K, Rafiee Z, Ghaedi M, Ultrason. Sonochem., 33, 240 (2016)
  34. Dastkhoon M, Ghaedi M, Asfaram A, Jannesar R, Sadeghfar F, J. Colloid Interface Sci., 513, 240 (2018)
  35. Asfaram A, Ghaedi M, Dashtian K, Ultrason. Sonochem., 34, 561 (2017)
  36. Yolmeh M, Habibi Najafi MB, Farhoosh R, Food Chem., 155, 319 (2014)
  37. Masrat R, Maswal M, Dar AA, J. Hazard. Mater., 244-245, 662 (2013)
  38. Lee DH, Cody RD, Hoyle BL, Can. Geotech. J., 38, 1329 (2001)
  39. Patil DM, Akamanchi KG, Ultrason. Sonochem., 37, 582 (2017)
  40. Perrier A, Delsart C, Boussetta N, Grimi N, Citeau M, Vorobiev E, Ultrason. Sonochem., 39, 58 (2017)
  41. Amiri-Rigi A, Abbasi S, Food Chem., 197, 1002 (2016)
  42. Sharma S, Kori S, Parmar A, Food Chem., 185, 284 (2015)
  43. Khan F, Siddiqui US, Rub MA, Khan IA, Kabir ud D, J. Mol. Liq., 191, 29 (2014)
  44. Yan MM, Chen CY, Zhao BS, Zu YG, Fu YJ, Liu W, Efferth T, Bioresour. Technol., 101(19), 7462 (2010)