A novel A-site deficient ceramic oxide (PrBa)(0.95)(Fe0.9Nb0.1)(2)O5+delta with layered perovskite structure has been investigated as an anode material for a direct-hydrocarbon fueled solid oxide fuel cell. Promising performance of this anode is achieved by stabilizing the material with Nb doping at B sites, which shows excellent chemical stability and high catalytic activity in the reducing fuel condition. The button cell based on lanthanum gallate electrolyte exhibits peak power density of 1.05 W cm(-2) in H-2, 0.64 W cm(-2) in CH4 (similar to 3% H2O) and 0.57 W cm(-2) in dry CH4 at 800 degrees C, respectively. When the temperature is decreased to as low as 600 degrees C, the cell still reaches 0.18 W cm(-2) in hydrogen. The anode is highly resistant against redox cycling with capability of rapid recovery from oxidizing condition. Based on a series of performance durability tests under various fuel conditions, this anode material has been demonstrated to be feasible for long-term operation in dry CH4 without observable degradation. The results demonstrate a new technical route to develop highly active and stable ceramic anode by doping high-valence rare-earth elements into B sites of perovskite material.