Hydrogen (H-2) production through water electrolysis is widely discussed as a means of storing renewable electricity in chemical bonds. Hydrogen can be used for transportation in fuel cell vehicles, but it can also be reacted with carbon dioxide (CO2) to form other fuels. While many concepts have been proposed, detailed comparisons of different pathways are still scarce. Herein, we present a technical, environmental, and economic comparison of direct H-2 use in fuel cells, and production of methane, methanol, and dimethyl ether (DME) for use in internal combustion engines for light-duty vehicle applications. The scenario considered uses renewable electricity for water electrolysis, and CO2 which is supplied continuously from biogas upgrading. All four fuels enable significant reductions (79-93%) in well-to-wheel greenhouse gas emissions as well as pollutant formation compared to fossil fuels, but they require very cheap H-2 to be competitive to fossil fuels, confirming intuitive expectations. While direct use of H-2 has obvious advantages (no conversion losses, high efficiency of fuel cells compared to internal combustion engines) in terms of overall electricity consumption, emissions, and fuel cost, its drawbacks compared to the other fuels are the need for an H-2 infrastructure, the high fueling pressure, and lower driving range. Among the three combustion engine fuels, DME has the lowest fuel cost and electricity consumption per distance driven because of the more efficient use of H-2 in its production, as well as the highest volumetric energy density, while methane has slightly lower greenhouse gas emissions. Cost and energy demand are dominated by H-2 supply, meaning that integrated solutions could be more attractive than separate electrolysis and fuel production.