A series of vanadia-titania catalysts with different vanadia loadings for the selective catalytic reduction (SCR) of NO by ammonia was prepared via incipient impregnation method. The alkali resistance and SCR activity at low temperature has been investigated on the prepared catalysts. Increasing the vanadia loading from 1% to 10%, the NO removal efficiency of the catalysts gained a 70% growth at 200 degrees C. With the increase of the vanadia loading, the high loading vanadia-titania catalysts exhibited higher ratio of V-5(+)/(V4++ V5+), which enhanced the oxidation of NH3 at high temperatures and also improved the standard SCR performance at low temperature. After doping with potassium, V-4/Ti catalyst (V2O5 = 4 wt%) displayed the best performance over which 80% initial activity was retained from 300 degrees C to 400 degrees C. More acid sites and active vanadium species were retained in the high loading vanadia-titania catalysts, which made them exhibit better low temperature alkali resistance. However, when vanadia content was higher than 4%, the competition of NH3 oxidation severely deactivated the catalytic activity above 250 degrees C. Additionally, in the presence of SO2 and H2O the SCR performance of the high loading vanadia-titania catalysts were also studied in order to investigate the influence of the actual working conditions.