This review emphasizes the importance of costs in industrial-scale treatment of dye wastewater and provides a way to assess the cost-based feasibility of bio-adsorption technologies. Dye wastewater is one of the major contributors to environmental pollution. Bio-adsorption has attracted considerable attentions in dye wastewater treatment due to its technical feasibility, flexibility and operation simplicity. However, industrial-scale treatment of dye wastewater via bio-adsorption technologies remains stagnant, mainly due to high costs. So far, no review or research articles have systematically discussed the criteria for successful utilization of bio-adsorption technologies on a large scale. This review discusses the major factors affecting adsorption and desorption performance based on basic chemical and physical structures of bio-adsorbents available in literatures. A quantitative relationship has been summarized based on previous studies to assess the cost to utilize a bio-adsorption technology and serve as an access threshold for quality bio-adsorbents to be taken into real applications.