Four novel biologically significant Zn (II) Schiff base complexes ([Zn(L-1)(2)](ClO4)(2) (1), [Zn(mu-fumarate)(L1)](n) (2), [ZnL1(N-3)(2)] (3) and [ZnL2(N-3)(2)] (4) were synthesized from two ligands L-1 [N-1,N-1-dimethyl-N-2-(1-(pyridine-2-yl)ethylidene)ethane-1,2-diamine]and L-2 [N-1,N-1-diethyl-N-2-(1-(pyridine-2-yl)ethylidene)ethane-1,2-diamine]. Detailed electrochemical polarization and impedance studies prove that corrosion inhibition activity of newly synthesized zinc complexes in 15% HCl on mild steel gets enhanced significantly due to the incorporation of psudo-halide azide as co-ligand. Different microscopic images (FE-SEM and AFM) depicted that metal surface is protected by Zn(II) complexes. Antibacterial activity of these Zn (II) azido Schiff base complexes against Grampositive Staphylococcus aureus was studied and reported. Further, antiproliferative activities of these azido complexes were studied against breast cancer cell line MCF 7.