Dissipative particle dynamics (DPD) simulations were applied to investigate the solution self-assembly and pH-responsive behavior of hydrophobic DCPD (dicyclopentadiene)-loaded microcapsules from triblock copolymers poly (1,2-ethanediol, homopolymer-b-2-Diethylaminoethylmethacrylate-b-methyl methacrylate) (PEG-b-PDMAEMA-b-PMMA). Results indicate that micelles with longer hydrophilic PEG blocks and shorter hydrophobic PMMA blocks were in favor of encapsulating hydrophobic DCPD. Cross-linking at the core/shell interface generates a chemically bonded network structure in the micelle and leads to a significant decrease of their thermodynamic mobility (i.e., the increase of stability). Both non cross-linked and cross-linked micelles show a good pH-responsive behavior. In particular, cross-linked micelles still have the ability to carry DCPD due to the incomplete dispersion even completely pro-tonation of PDMAEMA, which indicates that the cross-linked micelles could be expected to realize the slow release of encapsulated DCPD agent. (C) 2018 Elsevier Ltd. All rights reserved.