The ignition and combustion of H-2-O-2 mixture upon the photodissociation of O-2 molecules by the resonance laser radiation with a wavelength of 193 nm are studied both experimentally and computationally. The experimental test bench equipped with CARS and fluorescent diagnostic techniques was created and applied for the measurement of the induction time and velocity of combustion front during laser-induced ignition of the H-2-O-2 mixture in the model chamber. The complementary experiments on measuring the temperature and recording the emission of OH(X-2 Pi)and OH(A(2)Sigma(+)) radicals indicate that it is possible to ignite the H-2-O-2 mixture with phi=1-3 and P-0 = 1-3 atm at a rather low temperature similar to 700K, which is below the autoignition temperature, under the action of focused laser radiation(lambda = 193 nm) with the energy in the pulse of similar to 25-150 mJ. And the induction time is rather small and varies in the range of 8-50 mu s depending on mixture parameters and laser pulse energy. The analysis of ignition and combustion processes in the H-2-O-2 mixture under the action of resonance laser radiation is carried out on basis of two-dimensional numerical simulation with the use of the detailed kinetic mechanism of H-2 oxidation supplemented by the set of reactions describing the formation of electronically excited radicals OH(A(2)Sigma(+)). A special methodology for the calculation of the radiation absorption and determination of oxygen atoms concentration along the laser beam path was applied. The elaborated model allows us to describe the experimentally measured data for the induction time, the velocity of the combustion front, the space-time distribution of the OH radicals in the ground and excited states, and the temperature evolution in the focal region of the initiating laser radiation. (C) 2018 The Combustion Institute. Published by Elsevier Inc. All rights reserved.