Journal of the American Chemical Society, Vol.116, No.14, 6461-6462, 1994
Chemical and Structural Comparison of N-BOC-Cbq and N-BOC-CBI - Identification and Structural Origin of an Unappreciated But Productive Stability of the CC-1065 and Duocarmycin SA Alkylation Subunits
Keywords:ENHANCED FUNCTIONAL ANALOGS;(+)-CC-1065 DNA ALKYLATION;LEFT-HAND SUBUNIT;NONCOVALENT BINDING SELECTIVITY;1;2;9;9A-TETRAHYDROCYCLOPROPA(C)BENZ(E)INDOL-4-ONE CBI;ELECTROPHILE REACTIVITY;SEQUENCE SPECIFICITY;COMMON PHARMACOPHORE;CYCLOPROPANES;STREPTOMYCES