The thermophysical properties (density, speed of sound, viscosity and refractive index) for the binary mixtures of n-hexadecane with n-propylbenzene and sec-butylbenzene, were measured at temperatures in the range of (298.15-318.15) K and pressure of 0.1 MPa. The obtained experimental results were used to calculate the excess and deviation quantities, namely the excess molar volumes, the excess speed of sound, the excess isentropic compressibilities, excess molar isentropic compressibility, the deviation in viscosities, the deviation in refractive indices, and the excess molar refractions. The correlation of these excess properties was made by help of the Redlich-Kister type polynomial expression. The experimental viscosity values were compared with those calculated by using several different equations: Grunberg-Nissan, Katti Chaudry, Hind, Dolezalek, and three-body McAllister interaction model. Some theoretical (n,p) mixing rules (Lorentz-Lorenz, Gladstone-Dale, Arago-Biot, Edwards and Eykman) usually used in predicting the refractive indexes were assessed. The experimental and calculated results are discussed from the point of view of the molecular interactions between components of mixtures and their structural effects. (C) 2018 Elsevier Ltd.