Multifunctional materials, which can effectively and simultaneously remove various water-soluble contaminants like dyes and heavy metal ions, and separate oil from water, are urgent to meet increasing challenges on wastewater remediation. Herein, a cross-linked poly (acrylic acid) (PAA) modified poly (ether sulfone) nanofibrous membrane (NFM) was fabricated by a facile in-situ pre-reaction followed by electrospinning. The as-prepared NFM showed excellent hydrophilicity and underwater lipophobicity, therefore expressed excellent water permeability with high water flux (about 5142 L m(2) h(-1) ). As a result, under solely driven by gravity, the NFM was capable to separate emulsified oil/water emulsion and a wide range of oil/water mixtures. Moreover, repeating separation tests indicated that the NFM had great long-term sustainability even after ten separation cycles. In addition, due to the introduction of PM and the large surface-to-volume ratio, the NFM also expressed rapid adsorption capacity for cationic dyes as well as heavy metal ions; thus could simultaneously remove these contaminants during the oil/water separation process. Furthermore, the NFM could be also decorated by Ag NPs to endow the membranes with remarkable antibacterial ability against both E. coli and S. aureus. Our findings strongly suggested that the multifunctional NFM may have great potential in treating complicated wastewater. (C) 2018 Elsevier Inc. All rights reserved.