During electro-oxidation (EO) wastewater treatment, the applied voltage must polarize both a dimensionally stable anode with a sufficiently high potential to effectively produce hydroxyl radicals ((OH)-O-center dot), as well as a cathode with a sufficiently low potential to catalyze the H-2 evolution reaction (HER). Nevertheless, H-2 does not contribute to pollutant degradation and yet increases energy consumption. Inspired by fuel cell technology, in which the O-2 reduction reaction (ORR) is catalyzed on the cathode, herein, a carbon nanotube-coated carbon-PTFE gas diffusion electrode was fabricated to catalyze ORR during EO for the treatment of leachate concentrates. In comparison to conventional HER-EO, ORR-EO was shown to save 17.7-23.2% energy consumption. Further, as the cathodic ORR byproduct, H2O2 can react with the ozone generated from the Ti/SnO2-Sb2O5 anode to catalyze the peroxone process, which enhances (OH)-O-center dot generation for the degradation of organic products. This in situ electro-peroxone process was determined by salicylic acid (OH)-O-center dot trapping and liquid chromatography. The novel simultaneous EO and in situ electro-peroxone process described herein has great application potential and economic merit in the degradation of refractory organics in wastewater.