Mixed oxide catalysts yMn-Zr-Ti (y/10/10 with y = 1, 3, 5, 7 and 9) for the selective catalytic reduction (SCR) of NOx with NH3 in the presence of oxygen were synthesized by co-precipitation. The catalyst 5Mn-Zr-Ti exhibited a catalytic activity higher than 87% above 160 degrees C and N-2 selectivity above 92% at 100-300 degrees C. The SCR performance was quite stable at 180 and 200 degrees C for 15 h. Mn species are shown to improve the catalytic activity by providing more surface labile oxygen, while a synergistic effect among Mn, Zr and Ti species suppressed the generation of N2O. According to in situ DRIFT analysis, NOx was primarily reduced by the reaction of bidentate nitrate and monodentate nitrito species with adsorbed NH3. Subsequently, a comprehensive reaction mechanism was proposed. Accordingly, the formation of NH species was inhibited, and hence, the N2O formation by the reaction of NH and bidentate nitrate was suppressed. Furthermore, the investigation of the deactivation mechanism by SO2 indicated that both the deposition of ammonium sulfates and the sulfation of Mn active sites resulted in the deactivation of the catalyst 5Mn-Zr-Ti. The deposition of ammonium sulfates at 180 degrees C was more pronounced than that at 220 degrees C.