While quinone proton coupled electron transfer (PCET) under buffered conditions is well understood, the situation is more complicated in unbuffered aqueous solutions. With a view to producing a quinone-based voltammetric pH electrode that can function universally in both buffered and unbuffered solutions by following a two-electron (2e(-))/two-proton (2H(+)) Nernstian pathway over a wide pH range, the voltammetric response of strongly electronically coupled surface-bound quinones, directly integrated into a boron-doped diamond (BDD) electrode, is investigated. A laser ablation process enables integration of quinones into the BDD electrode surface with a high pK(a1) (first protonation state) and with controllable, very low surface coverages (as low as 2 orders of magnitude below monolayer coverage). Under buffered conditions, one wave results for all pH values, and the 2e(-)/2H(+) pathway is followed across the entire pH range. The measured ET rate constant values, from Laviron analysis, are also high, indicative of fast ET pathways. Under unbuffered conditions, one wave is again observed for all pH values; however, deviations from the buffered 2e(-)/2H(+) behavior are seen in the neutral region (pH 6-8). While 2e(-)/2H(+) transfer is maintained at all times, we attribute the observed deviation to local pH changes caused by the consumption and generation of protons at the electrode surface during the redox electrochemistry of the quinone. The associated proton fluxes generated at such sparse surface coverages are thought to be sufficiently high enough to prevent ET from occurring exclusively via a proton-independent route. By reducing surface coverage (down to similar to 4 x 10(-12) mol cm(-2); the limit of our laser ablation process) local pH changes can be reduced but are not eradicated completely. By moving to a pulsed voltammetric technique, where for each potential step protons consumed at the electrode are immediately replaced, it is possible, provided the surface coverage is low enough, to obtain a Nernstian 2e(-)/2H(+) response across a wide pH range in unbuffered solution.