This study investigates the impact of nine (9) metallic oxide nanoparticles (NPs) on ethanol production by Saccharomyces cerevisiae BY4743. Ethanol concentrations decreased at higher NPs (above 0.02wt%) for all the NPs studied. Ethanol production was mainly enhanced by Fe3O4 NPs with a maximum ethanol yield of 0.26g/g, glucose utilization of 99.95%, 0.22g/L/h ethanol productivity and 51% fermentation efficiency at 0.01wt%. The logistic and modified Gompertz kinetic models gave R-2 values0.88. The highest maximum specific growth rate ((max)), potential maximum ethanol concentration (P-m) and maximum production rate of 0.80h(-1), 5.24g/L and 0.72g/L/h were obtained with 0.01wt% NiO NPs and Fe-Ag NPs respectively. Nano inclusion in a simultaneous saccharification and fermentation (NISSF) process enhanced ethanol production from potato peels by 1.60-fold and 1.13-fold using NiO and Fe3O4 NPs respectively. These findings demonstrated the suitability of NiO and Fe3O4 NPs biocatalyst for their application in bioethanol production from agro waste such as potato peels. [GRAPHICS] .