The removal of NO from oxy-fuel combustion is typically incorporated in sour gas compression purification process. This process involves the oxidation of NO to NO2 at a high pressure of 1-3 MPa, followed by absorption of NO2 by water. In this pressure range, the NO conversion rates calculated using the existing kinetic constants are often higher than those obtained experimentally. This study aimed to achieve the regression of kinetic parameters of NO oxidation based on the existing experimental results and theoretical models. Based on three existingNO oxidationmechanisms, first, the expressions for NO conversion against residence time were derived. By minimizing the mean-square errors of NO conversion ratio, the optimum kinetic rate constants were obtained. Without considering the reverse reaction for NO oxidation, similar mean-square errors for NO conversion ratio were calculated. Considering the reverse reaction for NO oxidation based on the termolecular reaction mechanism, the minimummean-square error for NO conversion ratiowas obtained. Thus, the optimum NO oxidation rate in the pressure range 0.1-3 MPa can be expressed as follows: -d[NO]/dt = d[NO2]/dt = 0.0025[NO](2)[O-2]-0.0034[NO2](2) Detailed elementary reactions for N-2/NO/NO2/O-2 system were established to simulate the NO oxidation rate. A sensitivity analysis showed that the critical elementary reaction is 2NO + O-2 reversible arrow 2NO(2). However, the simulated NO conversions at a high pressure of 10- 30 bar are still higher than the experimental values and similar to those obtained from the models without considering the reverse reaction for NO oxidation. (C) 2018 The Chemical Industry and Engineering Society of China, and Chemical Industry Press Co., Ltd. All rights reserved.