In this short communication, we redefine smartphone and enable it to monitor blood glucose as glucometer. The proposed smartphone is not only a mobile phone but also a medical device-glucometer. An electrometer module, acquiring the electrochemical current from the disposable enzymatic test strip on which a 0.5 mu L human peripheral whole blood drop is placed, was integrated in the smartphone. The medical smartphone is capable of directly measuring blood glucose concentration and uploading into personal health center by the 4G mobile communication internet.