Yttria-stabilized zirconia hollow fibers (YSZ-HFs) containing radial wall microchannels with one end opening on the inner surface were prepared, and robust reactor modules of YSZ-HFs for automotive emission were prepared by bundling fibers with cement glue. 100% open-cell ratio and the unique microstructure of the YSZ-HFs catalytic reactor facilitated deposition of LaMnO3 three-way catalysts. Compared with the commonly used cordierite (2MgO2A1(2)O(3)-5SiO(2)) honeycombs (CHs), the YSZ-HFs improved the reducibility and sintering resistance of the attached catalyst film. Higher effective conversion of CO and NO was found in the YSZ-HFs samples in comparison to the CHs samples. Moreover, the YSZ-HFs samples achieving higher flexural strength (similar to 135 MPa) can better preserve the mechanical properties and the integrity of the catalyst film after 200 thermal shock cycles at 900 degrees C, due to the small thermal mismatch between the YSZ-HFs and the catalysts, as well as the intrinsic merit of zirconia.