Wall-coated Methane Steam Reformers (MSR) are commonly used as fuel processing in the hydrogen production chain. In such devices, the catalyst which is generally nickel-based is coated on the walls, and the heat supply influences directly the fuel processing efficiency. In this work, two-dimensional CFD study is carried out to explore an enhancement on MSR thermal behavior. Two configurations in terms of catalyst coating are investigated. The first MSR configuration is equipped with continuous catalytic layer, while in the second, discrete catalyst layers separated by an inert gap are imposed. The effect of the catalyst patterning on the thermal and mass behavior of MSR is discussed. The results show that the MSR efficiency can be improved by extending the catalytic zone and discretizing the catalyst coating. Comparing to conventional MSR with continuous catalytic layers, enhancement of 28.71% in CH4 conversion and 88.574% in H-2 production is realized by using discretized catalytic layers. (C) 2018 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.