The paper presents a survey of the interactive optimization cycle at Aachen University of Applied Sciences, used for the development of a new low emission Micromix combustor module for application in hydrogen fueled industrial gas turbines. During the development process, experimental and numerical methods are applied to optimize a given baseline combustor with 0.3 mm nozzles with respect to combustion efficiency, combustion stability, higher thermal power output per nozzle and reduced manufacturing complexity. Within the described research cycle combustion and flow simulations are used in the context of parametric studies for generating optimized burner geometries and the phenomenological interpretation of the experimental results. Experimental tests, carried out on an atmospheric combustion chamber test stand provide the basis for validation of simulation results and proof of the predicted combustion characteristics under scaled down gas turbine conditions. In the presented studies, an integration-optimized Micromix combustor with a nozzle diameter of 0.84 mm is tested at atmospheric pressure over a range of gas turbine operating conditions with hydrogen fuel. The combustor module offers an increase in the thermal power output per nozzle by approx. 390% at a significant reduced number of injectors when compared to the baseline design. This greatly benefits manufacturing complexity and the robustness of the combustion process against fuel contamination by particles. During atmospheric testing, the optimized combustor module shows satisfactory operating behavior, combustion efficiency and pollutant emission level. Within the evaluated operating range, which correlates to gas turbine part-, full- and overload conditions, the investigated combustor module exceeds 99% combustion efficiency. The Micromix combustor achieves NOx, emissions less than 2.5 ppm corrected to 15 Vol% O-2 at the design point. Based on numerical analyses and experimental low pressure testing, a full-scale gas turbine combustion chamber is derived. High pressure testing in the auxiliary power unit Honeywell/Garrett GTCP 36-300 shows stable operation during acceleration of the engine, during IDLE and during load variations between IDLE and Main Engine Start (MES) mode. Throughout the investigated operating range, the combustion chamber generates low NOx emissions under full-scale gas turbine conditions. (C) 2019 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.