The use of bioglass (BG) has been proved to be an effective strategy for reducing the sintering temperature and improving the degradability of bioceramics. In this work, a Na2O-CaO-MgO-P2O5 bioglass with a low melting temperature and an average particle size of 1.3 mu m and crystalline beta-tricalcium phosphate (beta-TCP) with an average particle size of 600 nm were first prepared separately. 3D printing was then used to fabricate the beta-TCP/BG composite porous ceramic scaffolds. The Na2O-CaO-MgO-P2O5 bioglass-reinforced beta-TCP porous ceramic scaffolds demonstrated a significant enhancement in their mechanical properties, degradability and biocompatibility compared with pure beta-TCP ceramics. The results showed that the compressive strength and elastic modulus of the reinforced beta-TCP ceramic scaffold were 8.34 MPa and 208.5 MPa, respectively, and the degradation rate of the beta-TCP porous ceramic scaffolds increased by a factor of 2.99. In addition, the optimized scaffold distinctly promoted MC3T3-E1 osteoblast cell proliferation. Na2O-CaO-MgO-P2O5 bioglass-reinforced beta-TCP porous ceramic scaffold has great potential for application in bone regeneration.