The dielectric relaxation and conduction properties of hexaferrite BaFe10.2Sc1.8O19 (BFSO) ceramics have been investigated by impedance spectroscopy (1Hz-2GHz) at various temperatures (253-473K). The frequency dependence of impedance and modulus spectra of BFSO shows that its dielectric responses are thermally activated. The scaling behaviors of impedance spectra indicate that the distribution of dielectric relaxation times in BFSO is temperature independent. The frequency-dependent conductivity spectra follow the universal-power-law at high temperatures but deviate slightly at low temperatures. An enormous increase in relaxation/conduction activation energies of BFSO above 413K is also observed in both impedance and conductivity spectra. This indicates that at high temperatures, relaxation/conduction processes may be contributed mainly by the movable oxygen vacancies, whereas at low-temperature electron hopping dominates. The conductivity fitting results further suggest that electron/oxygen vacancy-related small polaron hopping should be the most probable conduction mechanism for BFSO.