The growth of pinholes generated in coated films of adhesives was simulated numerically. Rheological properties of the adhesives were approximated by a power-law model. The motion of the interface of the adhesives was traced by a VOF method. Simulated results were in good agreement with experimental ones. The growth rate was proportional to the inverse of Ohnesorge number and therefore decreases when the viscosity of the adhesives is high and the surface tension is low.