Increasing the efficiency of cross-coupling reaction under mild condition and easy catalyst separation is a key issue in the realistically chemical industry application. Here, we report that the fiber-supported Pd catalyst shows a high activity and selectivity for the cross-coupling reaction of terminal alkynes. The yield of the asymmetric 1,3-diyne can reach 83% at 80 degrees C and 4h reaction time in N,N-dimethylacetamide (DMAc), and about 87% selectivity. XPS, EDS and SEM results show that Pd metal ions are successfully loaded onto the fiber surface and are reduced to produce active component of Pd (0) by terminal alkyne in reaction. We consider that Pd (0) is the active center of the catalytic cycle, the coordination of the fibers can stabilize Pd particles on the supports and increases the catalytic activity of Pd catalysts. Cu (I) plays a synergistic catalytic role. This study provides an alternative pathway for the high efficient cross-coupling reaction. [GRAPHICS] .