The operators of chemical technologies are frequently faced with the problem of determining optimal interventions. Our aim is to develop data-driven models by exploring the consequential relationships in the alarm and event-log database of industrial systems. Our motivation is twofold: (1) to facilitate the work of the operators by predicting future events and (2) analyse how consequent the event series is. The core idea is that machine learning algorithms can learn sequences of events by exploring connected events in databases. First, frequent sequence mining applications are utilised to determine how the event sequences evolve during the operation. Second, a sequence-to-sequence deep learning model is proposed for their prediction. The long short-term memory unit-based model (LSTM) is capable of evaluating rare operation situations and their consequential events. The performance of this methodology is presented with regard to the analysis of the alarm and event-log database of an industrial delayed coker unit. (C) 2019 Elsevier Ltd. All rights reserved.