In this study, parabolic trough collector with an integrated source of geothermal water is used with regenerative Rankine cycle with an open feedwater heater, an electrolyzer, and an absorption cooling system. The absorption fluids used in the solar collectors were Al2O3- and Fe2O3-based nanofluids. Detailed energetic and exergetic analyses are done for the whole system including all the components. A comparative analysis of both the used working fluids is done and plotted against their different results. The parameters that are varied to change the output of the system are ambient temperature, solar irradiance, the percentage of nanofluids, the mass flow rate of the geothermal well, the temperature gradient of the geothermal well that had an effect on the net power produced, and the outlet temperature of the solar collector overall energetic and exergetic efficiencies. Other useful outputs by this domestic integrated multigeneration system are the heating of domestic water, space heating (maintaining the temperature at 40 degrees C-50 degrees C), and desalination of seawater (flash distillation). The hydrogen production rate for both the fluids diverges with each other, both producing average from 0.00490 to 0.0567 g/s.