Journal of the American Chemical Society, Vol.118, No.32, 7529-7541, 1996
Oligoanthranilamides - Nonpeptide Subunits That Show Formation of Specific Secondary Structure
A family of novel oligomers based on the anthranilamide nucleus has been prepared and shown to form well-defined secondary structural features. H-1 NMR and X-ray crystallographic techniques have demonstrated that intramolecular hydrogen bonds play a key role in stabilizing both linear sheet and helical conformational forms.
Keywords:ANTHRANILIC ACID PEPTIDES;MOLECULAR SCAFFOLDS;HELICAL MOLECULES;CRYSTAL-STRUCTURE;AM1 DESCRIPTION;CONFORMATION;COMPLEXES;CHEMISTRY;FAMILY;BACKBONE