When raw sour gas is gathered for transportation over long distances, adsorptive dehydration is often employed to avoid condensable water prior to purification at a gas processing plant, i.e., adsorptive dehydration is used to avoid excessive corrosion or hydrate plugging within transportation/gathering lines. To optimize and design adsorptive conditioning facilities, simulation requires self-consistent experimental adsorption measurements at pressures relevant to gathering and transportation. To this end, manometric adsorption measurements on methane, carbon dioxide, carbonyl sulfide, and hydrogen sulfide on silica gel were measured at high pressures. This data adds to our previous work with sour gas adsorption on zeolites 4A and 13X. Also, in this study, gravimetric measurements for water adsorption are reported for silica gel, zeolite 3A, and zeolite 4A. Absolute and excess adsorption isotherms were determined for the adsorptives studied with operating temperatures ranging from T = 0 to 50 degrees C and T = 25 to 150 degrees C for the manometric and gravimetric measurements, respectively. Across all of the desiccant materials studied, H2O has the largest adsorption affinity, followed by the acid gases (H2S and CO2), COS, and finally CH4. In terms of H2O adsorption, zeolites 3A and 4A show similar affinity (low-pressure Henry's law slope), whereas zeolite 4A shows a slightly larger capacity. Both zeolites 3A and 4A exceed silica gel in terms of capacity and affinity.