Silver clusters were assembled in helium droplets of different sizes ranging from 10(4) to 10(11) atoms. The clusters were heated upon laser irradiation at 355 nm, and evaporation dynamics of He atoms were studied by quadrupole mass spectroscopy using signals from He+, He-2(+), and He-4(+) splitter ions. We found that for droplets containing less than 10(7) atoms the laser irradiation leads to evaporation of He atoms. However, the laser irradiation leads to the breakup of the large droplets into smaller ones.