Crystal structure modification was introduced into CdWO4 via La doping strategy and the characterization results of SEM, XRD, TEM and EDS confirmed the morphology, crystal phase structure and composition of the CdWO4 and La-doped CdWO4 nanorods. Meanwhile, the partial substitution of Cd by La ions in CdWO4 nanocrystal was confirmed via some classic formulas. Excellent electrocatalytic performance was obtained on the electrochemical sensing interface when the La ions were doped into the CdWO4 lattice. The exquisite and regular rod-like 1.0% La-doped CdWO4 nanorods modified electrochemical sensor was established and applied to detect BPA with a highly sensitive detection limit (2.0 x 10(-8) M). The more excellent electrocatalytic activity of 1.0% La-doped CdWO4 than other doping ratio nanomaterials was verified. The possible mechanism of the electrochemical catalysis of BPA was proposed based on the effective electrochemical analysis methods (EIS, CV and I-t) and the deductions from various physicochemical characterizations. More electron transmission channels were formed in the crystal due to the moderate amount of La ions in CdWO4 nanorods. Unprecedently, electrocatalytic performance of nanomaterials can be more efficiently promoted through regulating the doping atmosphere of crystal within the materials. This novel strategy will potentially provide a significant reference for solving the related electrocatalysis and electrochemical sensing interface's problems. (C) 2019 Elsevier Ltd. All rights reserved.