Vaporizers are the key heat transfer device in the regasification process of liquefied natural gas (LNG), especially for the conventional onshore LNG receiving stations. This paper has proposed a novel intermediate fluid vaporizer by employing multi-stream plate-fin heat exchanger (MPFHE-IFV). Compared to traditional shell-and tube IFVs, it can not only achieve a higher heat transfer efficiency with more compact structure using MPFHE but also realize the recovery and reuse of LNG cold energy with intermediate fluid. In this ingenious design, the self evaporating gas of cryogenic liquid is adopted as the intermediate medium of IFV so that the equipment freezing can be effectively avoided under large flow conditions. A thermal-hydraulic design model has been established for MPFHE-IFV to determine the detailed structural dimensions as well as the heat transfer performance, and a corresponding multi-objective optimization algorithm has been adopted to obtain the minimum equipment volume, the optimal channel arrangement and fin structure, the maximum cold energy recovery efficiency and the optimal number of internal cycles. Meanwhile, the transmission process of the cryogenic exergy in MPFHE-IFV has been revealed according to the analysis of the system temperature-entropy diagram. Finally, two experimental cases based on the liquid nitrogen regasification process are conducted to evaluate the practical performance of the novel MPFHE-IFVs using the design and optimization method proposed in this paper. The results indicate that this new type of IFV can reach the highest cold energy recovery efficiency up to 95% within the 8% error range when the heat transfer capacity is 11.5 kW and the heat medium flow rate is near 330 L/h.