The current chemical industry has been heavily optimized for the use of petroleum-derived base chemicals as its primary source of building blocks. However, incorporation of heteroatoms, absent in the base chemicals, is necessary to meet the different property requirements in the plethora of products the industry makes such as plastics, cosmetics, and pharmaceuticals. As global oil reserves deplete, a shift toward renewable bioderived building blocks, so-called platform molecules, will become a necessity. Bioderived platform molecules are typically rich in heteroatoms as a result of their biomass feedstock also being heteroatom rich, and it would therefore seem logical to carry these heteroatoms through to the aforementioned products. A tool was herein developed to assess the rationality of a synthetic route from feedstock to product, designed specifically to give a visual representation of the pathways and options available. BioLogicTool plots (%heteroatom by mass vs M) are an alternative to the conventional van Krevelen diagram, and are designed to better consider the diversity in heteroatom content encountered in biobased chemicals. The tool can rapidly help its user to design more logical multistep synthetic routes and enhance the mass efficiency of pathways. Several examples were selected to demonstrate the power and limitations of the BioLogicTool, but it was clear from these examples that removing heteroatoms from platform molecules to reincorporate them later in the final product is, in most cases, not logical in a mass efficiency sense.