Metal and nitrogen co-doped catalysts have been promising alternatives to platinum group metal (PGM) catalysts for oxygen reduction reaction (ORR) over the past few decades. Herein, we have synthesized an efficient Fe-N-C catalyst by the co-calcination of NH2-MIL-101@PDA and melamine. The best Fe-N-C shows a positive half-wave potential of 0.844 V, which is 14 mV higher than that of Pt/C catalyst, as well as superior methanol resistance and long-term durability in alkaline electrolyte. In addition, Fe-N-C also exhibits pronounced catalytic activity and a direct 4e(-) reaction pathway in acid electrolyte. We ascribed the excellent ORR performance of Fe-N-C to its crumpled structure, large specific surface area (584.6 m(2) g(-1)) and high content of Fe-Nx sites (1.22 at. %). This study provides a simple way for the fabrication of excellent PGM-free ORR catalysts. (C) 2019 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.