The purpose was to evaluate solubility data and solute-solvent molecular interactions of 5-aminotetrazole in various pure solvents including methanol, ethanol, n-propanol, isopropanol, 1-butanol, toluene, acetone, acetonitrile, ethyl acetate, 1,4-dioxane, N,N-dimethylformamide (DMF), and N-methyl pyrrolidone (NMP) at temperatures "T = 283.15-323.15 K" and pressure "P = 0.1 MPa". Solubility data were determined by the isothermal saturation method with the help of high-performance liquid-phase chromatography. Solubility data of 5-aminotetrazole obtained in mole fraction showed the maximum value in DMF (7.951 X 10(-2)), followed by NMP (7.415 X 10(-2)), 1,4-dioxane (6.523 X 10(-2)), toluene (3.811 X 10(-3)), isopropanol (1692 x 10(-3)), ethanol (1.752 X 10(-3)), acetone (1.620 X 10(-3)), n-propanol (1.566 X 10(-3)), methanol (1.470 X 10(-3)), ethyl acetate (1.393 x 10(-3)), 1-butanol (1.315 X 10(-3)), and acetonitrile (3.85 x 10(-4)) at T = 323.15 K. Moreover, properties of solvents such as the polarity and the Hildebrand solubility parameters were analyzed as well. The function of solubility values in pure solvents and the temperature were evaluated by the modified Apelblat equation and the lambda h equation. The maximum values of the relative average deviation and root-mean-square deviation are no more than 1.58 X 10(-2) and 4.43 X 10(-4), respectively, which indicated that good correlation was recorded between the experimental and calculated data. Then, the Akaike information criterion was used to select the more suitable model. Obtaining solubility data and correlative model parameters of 5-aminotetrazole and understanding the intermolecular forces in different solvents are particularly important in industrial synthesis and separation.