Materials Chemistry and Physics, Vol.232, 75-81, 2019
Fabrication of graphene incorporated biphasic calcium phosphate composite and evaluation of impact of graphene in the in-vitro biomineralization process
The objective of this work is to design and development of graphene based bioceramic composite. The composition of graphene bioceramic composite is Hydroxyapatite/beta-Tricalcium phosphate reinforced Graphene oxide (HAp/beta-TCP/GO). The crystalline structure, chemical composition, morphology and elemental analysis of the developed composite were characterized using analytical techniques such as X-Ray Diffraction (XRD), Fourier Transform Infra red (FTIR) Spectroscopy, Raman Spectroscopy, Field Emission Scanning Electron Microscopy (FESEM) and Energy Dispersive Spectroscopy (EDS). In order to investigate the effect of graphene oxide on the in-vitro bio mineralization, the developed composite was immersed in Simulated Body Fluid (SBF) solution for various time periods (0, 7, 14 and 21 days) and the results indicate that the reinforcement of graphene oxide promotes the growth of hydroxyl apatite layer on the surface of composite discs. Further the developed composite of beta-TCP/HAp reinforced graphene oxide can be used as a potential candidate material for biomedical applications.